Systemic Eye Diseases Part 01

Posted by e-Medical PPT
Uveitis can be defined as inflammation of the uvea, the middle, vascular coat of the eye.
Uvea consists of iris, ciliary body and the choroid.The ciliary body contains 2 parts:pars plicata (anterior) and pars planta (posterior).

Causes of anterior uveitis:
1-HLA positive or seronegative group:
           A-Ankylosing spondylitis.
           B-Reiter’s syndrome.
           C-IBD”Inflamatory bowel disease”.
           D-Psoriatic arthritis.
2-Systemic Infections “TB, HIV and syphilis”
3-Sarcoidosis, Behçet's disease , JRA.

Symptom of anterior uveitis
 * Redness of the eye
 * Blurred vision
 * Sensitivity to light (photophobia)
 * Dark, floating spots along the visual field
 * Eye pain

Phakomatoses (or "neurocutaneous syndromes") are disorders of central nervous system that additionally result in lesions on the skin and the retina which are:
  Type I (NF-1) - von Recklinghausen disease
  Type II (NF-2) - bilateral acoustic neuromas
Tuberous sclerosis
von-Hippel-Lindau syndrome
Sturge-Weber syndrome ’’encephalotrigeminal angiomatosis ‘’’

Intraocular lesions in NF-1:Lisch nodules,Retinal astrocytomas,Choroidal naevi ect

Ocular complications frequently occur in rheumatoid arthritis
The lacrimal glands
affected by an inflammatory process with consequent inadequate tear flow.
complains of: dry, gritty, and sore eyes.

Episclera  and sclera coats of the eye,
complain of: red, uncomfortable eye tenderness over the area.
Scleritis is usually much more painful than episcleritis and
the engorged vessels are deeper. If continues, the sclera
may become thin (scleromalacia) the eye may perforate.

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