Classification of malabsorption syndrome
Impaired intraluminal digestion
Intestinal malabsorption
Fermentation

In many cases  more factors elicit the malabsoprtion (e.g.bacterial overgrowth)

Malabsorption due to impaired intraluminal digestion
CF
Schwachman syndrome
Isolated lipase or colipase deficiency
Impaired bile acid synthesis
Bile duct atresia
Interrupted enterohepatic circulation
ileal resection
Crohn disease
Congenital malabsorption of bile acids
Congenitalis trypsinogen or enterokinase deficiency

Intestinal malabsorption
Coeliac disease
Sensitization to food proteins (cow’s milk, soya, rice, wheat)
Giardia infestation
Postenteritis syndrome
Immunodeficiency syndromes
Acrodermatitis enteropathica
Bacterial overgrowth
Crohn disease
Short bowel syndrome
Intestinal lymphangiectasia
Autoimmune enteropathy
Congenital microvillous atrophy
Selective transport defects

Symptoms of malabsorption
Chronic diarrhoea (longer than two weeks)
Slowened weight gain or weight loss
Abdominal distention
Decreased turgor
Vomiting
Anaemia (iron deficiencient or megaloblastic)
Oedema
Symptoms of secondary vitamin deficiencies (rickets, bleeding,  hemeralopia)

Suggested laboratory investigations
Blood test
Seum iron, transferrin, saturation, ferritin
Serum protein
Aminoacid chromatography
Immunoelectrophoresis
D-xylose loading test
alpha-1 antitrypsin content of stool
Serum bilirubin, bile acids
Serological tests (Antiendomysium, IgE antibodies against cow’s milk proteins)

Causes of villous atrophy
Postenteritis syndrome
Cow’s milk allergy
Soya allergy
Coeliac disease
Giardiasis
Immunodeficiency syndromes
Autoimmune enteropathy

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