Glomerulonephritis

Posted by e-Medical PPT
Features of Glomerular Disease
Proteinuria
Haematuria
Renal Failure
Salt and Water Retention results in Hypertension,Oedema and Oliguria
Loin Pain

Proteinuria
Frothing
Marker of renal disease
Risk factor for cardiovascular disease
Dyslipidaemia
Hypertension
Something more?
24 hr protein vs urine protein:creatinine ratio

eGFR and CKD
>50% inaccurate in over 50% patients
Worst hit: females over 60
Quadrupled our referral rate
Mostly inappropriate
Unnecessary worry for patients
Is it really necessary to refer a patient with a stable creatinine of 130 ╬╝mol/l just because you now know their eGFR is 40?

Common Syndromes
Nephrotic Syndrome
Nephritic Syndrome
Rapidly Progressive GN
Loin Pain Haematuria Syndrome

Nephrotic syndrome
Proteinuria (>3g/24 hr)
Hypoalbuminaemia (<30g/l)
Oedema
Hypercholesterolaemia
Thromboses
Infection

Nephritic Syndrome
Haematuria
Hypertension
Oliguria

Rapidly progressive GN
Nephritic or nephrotic onset
ESRF in six months

Loin pain haematuria syndrome
Bilateral or unilateral pain
Macroscopic or microscopic haematuria
Other “functional” disorders common
Young female healthcare professionals

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